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- W2362458229 abstract "OBJECTIVE To prepare the inclusion compound of propyl gallate-hydroxypropyl-β-cyclodextrin and increase the solubility of propyl gallate.METHODS Propyl gallate-hydroxypropyl-β-cyclodextrin was prepared by solution-stirring,the formation of inclusion was verified by powder X-ray diffraction,infrared spectrum,differential scanning calorimetry and phase solubility diagram studies.UV spectroscopy was established to determine the content of drug. RESULTS The molar ratio of host molecule to guest molecule was 1:1.Solubility was increased about 30 times by solubilization compared with documented solubility of propyl gallate.Apparent stability constant was 8372L·mol-1.CONCLUSION The inclusion compound was very stable,and solubility increased significantly." @default.
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- W2362458229 date "2006-01-01" @default.
- W2362458229 modified "2023-09-25" @default.
- W2362458229 title "Preparation of inclusion compound of propyl gallate-hydroxypropyl-β-cyclodextrin" @default.
- W2362458229 hasPublicationYear "2006" @default.
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