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- W2362474874 abstract "Objective To investigate the clinical efficacy and safety of prednisone combined with tripterygium glycosides in the treatment of adult purpura nephritis.Methods The patients(83 cases) diagnosed with adult purpura nephritis in Guiyang Hospital of Traditional Chinese Medicine from January 2011 to January 2013 were randomly divided into treatment(41 cases) and control(42 cases) groups.The patients in the control group underwent the auxiliary examination after admission,and they were administered with low-salt,low-protein,and low-fat diet.They were given albumin,heparin with low molecular weight,and kidneys supportive treatment,while they were po administered with prednisone(30 mg/d).The amount of prednisone was reduced eight weeks later,and the reduction rate was 2.5 mg per week,and finally 10 mg/d maintained the therapy.The treatment lasted for six months.The patients in the treatment group were po administered with tripterygium glycosides(20 mg) on the basis of control group,three times daily for eight weeks or more.After the treatment,the clinical efficacy and adverse reactions of the two groups were compared,and the average clearance times of proteinuria and hematuria,edema and hypertension disappearance times were compared.Results After the treatment,the efficacies in the treatment and control groups were 92.68% and 76.19%,respectively,with the significant difference between the two groups(P0.05).The average clearance times of proteinuria and hematuria,edema and hypertension disappearance times of the treatment group were significantly shorter than those of the control group(P0.05).There was no significant difference on the incidence of the adverse reactions between the two groups.Conclusion Prednisone combined with tripterygium glycosides in the treatment of adult purpura nephritis could significantly improve the clinical symptoms,which has a high total efficiency." @default.
- W2362474874 created "2016-06-24" @default.
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- W2362474874 date "2013-01-01" @default.
- W2362474874 modified "2023-09-24" @default.
- W2362474874 title "Clinical observation of prednisone combined with tripterygium glycosides in treatment of adult purpura nephritis" @default.
- W2362474874 hasPublicationYear "2013" @default.
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