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- W2362490318 abstract "Objective To study the expression of survivin、bcl-2 and p53 and its mutual correlation in nasopharyngeal carcinoma(NPC).Methods With our self-made nasopharyngeal carcinoma tissue microarrays,the expression of survivin、bcl-2 and p53 gene was detected by immunohistochemistry method.Results Survivin genes expression in nasopharyngeal carcinoma and the tumor surrounding epithelium were higher than in nasopharyngeal epithelium.Bcl-2 and p53 gene expression in nasopharyngeal carcinoma tissue were higher than in the tumor surrounding epithelium and nasopharyngeal epithelium.P53 gene expression was higher in the tumor surrounding epithelium than in the nasopharyngeal epithelium.Close correlation was found between the expression of survivin and bcl-2 and between the expression of survivin and p53 protein in nasopharyngeal carcinoma tissues.Conclusion Survivin、bcl-2 and p53 has a close relationship and a synergistic effect in the carcinogenesis and development of nasopharyngeal carcinoma." @default.
- W2362490318 created "2016-06-24" @default.
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- W2362490318 date "2004-01-01" @default.
- W2362490318 modified "2023-09-24" @default.
- W2362490318 title "Expression of Survivin、bcl-2 and p53 Protein and its Mutual Correlation in Nasopharyngeal Carcinoma" @default.
- W2362490318 hasPublicationYear "2004" @default.
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