Matches in SemOpenAlex for { <https://semopenalex.org/work/W2362552354> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W2362552354 endingPage "32C" @default.
- W2362552354 startingPage "25C" @default.
- W2362552354 abstract "The molecular mechanisms that regulate the function of the immune system and human immunodeficiency virus type-1 (HIV-1) gene expression are diverse and complicated. However, replication of HIV-1 is controlled by many of the same regulatory signals that play a crucial role in the transcriptional regulation of the immune system. For example, the viral promoter, as is the case for the immune system, is subject to complex regulation by combinations of cellular transcription factors that may quantitatively and/or qualitatively differ depending on cell types (eg, macrophages versus T lymphocytes) and cell states (eg, undifferentiated versus differentiated or quiescent versus activated). The present review discusses the regulation of HIV-1 gene expression by nuclear factor-kappa Band nuclear factor of activated T cells, and proposes that selective interference of these two cellular transcription factors may be a route to abrogate virus replication without disrupting normal cellular functions. A better understanding of the regulation of HIV-1 gene expression is of utmost importance for the design of molecular approaches that will effectively abrogate virus replication and, ultimately, disease progression." @default.
- W2362552354 created "2016-06-24" @default.
- W2362552354 creator A5002103013 @default.
- W2362552354 creator A5032402287 @default.
- W2362552354 creator A5039852039 @default.
- W2362552354 creator A5073259394 @default.
- W2362552354 date "1999-01-01" @default.
- W2362552354 modified "2023-09-27" @default.
- W2362552354 title "T Cell Activation and Regulation of HIV-1: Same Effectors with Distinct Outcomes" @default.
- W2362552354 doi "https://doi.org/10.1155/1999/717641" @default.
- W2362552354 hasPublicationYear "1999" @default.
- W2362552354 type Work @default.
- W2362552354 sameAs 2362552354 @default.
- W2362552354 citedByCount "0" @default.
- W2362552354 crossrefType "journal-article" @default.
- W2362552354 hasAuthorship W2362552354A5002103013 @default.
- W2362552354 hasAuthorship W2362552354A5032402287 @default.
- W2362552354 hasAuthorship W2362552354A5039852039 @default.
- W2362552354 hasAuthorship W2362552354A5073259394 @default.
- W2362552354 hasBestOaLocation W23625523541 @default.
- W2362552354 hasConcept C104317684 @default.
- W2362552354 hasConcept C140704245 @default.
- W2362552354 hasConcept C150194340 @default.
- W2362552354 hasConcept C165864922 @default.
- W2362552354 hasConcept C2522874641 @default.
- W2362552354 hasConcept C27153228 @default.
- W2362552354 hasConcept C51785407 @default.
- W2362552354 hasConcept C54355233 @default.
- W2362552354 hasConcept C86339819 @default.
- W2362552354 hasConcept C86803240 @default.
- W2362552354 hasConcept C8891405 @default.
- W2362552354 hasConcept C95444343 @default.
- W2362552354 hasConceptScore W2362552354C104317684 @default.
- W2362552354 hasConceptScore W2362552354C140704245 @default.
- W2362552354 hasConceptScore W2362552354C150194340 @default.
- W2362552354 hasConceptScore W2362552354C165864922 @default.
- W2362552354 hasConceptScore W2362552354C2522874641 @default.
- W2362552354 hasConceptScore W2362552354C27153228 @default.
- W2362552354 hasConceptScore W2362552354C51785407 @default.
- W2362552354 hasConceptScore W2362552354C54355233 @default.
- W2362552354 hasConceptScore W2362552354C86339819 @default.
- W2362552354 hasConceptScore W2362552354C86803240 @default.
- W2362552354 hasConceptScore W2362552354C8891405 @default.
- W2362552354 hasConceptScore W2362552354C95444343 @default.
- W2362552354 hasFunder F4320324195 @default.
- W2362552354 hasIssue "suppl c" @default.
- W2362552354 hasLocation W23625523541 @default.
- W2362552354 hasOpenAccess W2362552354 @default.
- W2362552354 hasPrimaryLocation W23625523541 @default.
- W2362552354 hasRelatedWork W1930517486 @default.
- W2362552354 hasRelatedWork W2026817254 @default.
- W2362552354 hasRelatedWork W2066804688 @default.
- W2362552354 hasRelatedWork W2074009497 @default.
- W2362552354 hasRelatedWork W2172226517 @default.
- W2362552354 hasRelatedWork W2363024816 @default.
- W2362552354 hasRelatedWork W2404327720 @default.
- W2362552354 hasRelatedWork W2927272475 @default.
- W2362552354 hasRelatedWork W2984359285 @default.
- W2362552354 hasRelatedWork W4281611476 @default.
- W2362552354 hasVolume "10" @default.
- W2362552354 isParatext "false" @default.
- W2362552354 isRetracted "false" @default.
- W2362552354 magId "2362552354" @default.
- W2362552354 workType "article" @default.