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- W2362558276 abstract "Objective:To study the dynamic level of plasma endotoxin(PE)levels in the patients with malignant obstructive jaundice during the perioperative period and clinical significance of cleaning intestinal tract by using the method of integrated traditional and western medicine.Methods:Forty-eight patients with malignant obstructive jaundice were prepared for operation were randomly divided into treatment group A (n=24) and control group B(n=24). Besides general preoperative preparation,Chinese herbs-Xiao-Cheng-qi decoction of orintal wormwood were taken and normal saline iodophor diluent enema were carried out in group A. Routine preoperative preparation were excuted in group B only. The kinetic changes of PE levels during the perioperartive period,hydrogen breath test (HBT) were examined and the incidence of postoperative complications,postoperative duration of ventilation,hospital day.Results:The PE baseline levels in two groups were 0.72±0.18 EU.mL-1 and 0.70±0.22 EU.mL-1 respectively(P0.05),and decreased to 0.55±0.21EU.mL-1and 0.67±0.13 EU.mL-1 after preoperative preparation (P0.05). The positive rates of HBT in two groups were 87.5% and 83.3%(P0.05),and decreased to 50.0% and 75.0% after preoperative preparation (P0.05). The incidence of SIRS,renal inadequacy in group A were 8.3%and 12.5%,lower than group B (P0.05). Postoperative duration of ventilation in group A (78.3±21.2)h were more abbreviated obviously than group B(138.4±42.5)h,and hospital during in group A (18.7±4.5) d were more abbreviated obviously than group B (30.3±3.7) d,too.Conclusion:The patients with malignant jaundice all have bacterial translocation from intestine and endotoxemia. The use of the therapy with dilute Povidone Iodine coloclysis and taking traditional herbal drug before operation can decrease the rate of endotoxemia and conduce to recovery of patients after operation." @default.
- W2362558276 created "2016-06-24" @default.
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- W2362558276 date "2009-01-01" @default.
- W2362558276 modified "2023-09-23" @default.
- W2362558276 title "Endotoxemia and It's Therapy for the Patients with Malignant Obstructive Jaundice during the Perioperative Period" @default.
- W2362558276 hasPublicationYear "2009" @default.
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