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- W2362575906 abstract "Objective To quantitatively analysis the DTI T2-weighted trace(T2-WT) parameter map in different age of healthy human brain and its relation to age.Methods Data were acquired in fifty-eight healthy right-handed volunteers(22-76 years).28 subjects in middle-old age group(40years) and 30 subjects in young group(≤40years).All subjects underwent diffusion tensor imaging(DTI) and conventional MRI with a GE 3.0T magnetic resonance system.Three DTI parameters T2-WT,fractional anisotropy(FA)and mean diffusivity(MD) were acquired from the MR work station.ROIs were determined at FA and MD maps.The ten structures T2-WT values were measured in the two groups.Quantitative analyzed the the T2-WT maps and its relation to age.Results In the young group,the value of T2-WT had a left-right asymmetries in pons,cerebral peduncle,anterior internal capsual,centrum seimioval and lenticular nucleus,leftright,P=0.000~0.024.Whereas in the middle-old age group,T2-WT values were lower than the young group except the lateral cerebral ventricle,and had a left superior only in centrum semioval(P=0.042).Significant negative correlation with age were found in pons,cerebral peduncle,three parts of the internal capsule and lenticular nucleus(P=0.000~0.038).Conclusion T2-WT parameter map is more symmetry in middle-old age group.In pons,cerebral peduncle,three parts of internal capsule and lenticular nucleus,T2-WT values have significant negative correlations with age." @default.
- W2362575906 created "2016-06-24" @default.
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- W2362575906 date "2012-01-01" @default.
- W2362575906 modified "2023-09-23" @default.
- W2362575906 title "Quantitative study of DTI T_2-weighted trace parameter map in healthy human brain and its relation to aging" @default.
- W2362575906 hasPublicationYear "2012" @default.
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