Matches in SemOpenAlex for { <https://semopenalex.org/work/W2362595255> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2362595255 abstract "Objective To determine the occurrence of cell dea th in situ in diabetic-like retinopathy from the streptozotocin (STZ)-induced diabetic rats after 6, 9, 12 months. Methods 90 male Sprague -Dawley rats were randomly divided into normal control group (n=30) and dia betic model group. STZ were used to induce diabetes in rats. Rats in each grou p were frequently examined with blood glucose and weight, and killed after 6, 9, 12 months(n=20). The sections prepared from the trypsin-digested retina w ere studies with periodic acid-schiff-hematoxylin stain. The terminal deoxynuc leotidyl transferase-mediated dUTP nick end labeling (TUNEL) reaction was used to detect the preferentially apoptotic DNA fragmentation. Results Retinal microvessels of 6 month diabetic rats showed TUNEL-positive pericy tes, which were absent in control rats. Retinal micrographs of 9, 12 month diab etic rats showed pericytes and endothelial cell apoptosis respectively with TUNE L reaction and PAS stain. At 12 months, the numbers of apoptotic endothelial ce lls were more, and each of the pictures showed TUNRL-positive endothelial cell or apoptotic bodies under the light microscope. Conclusions These findings indicate that diabetes leads to the accelerated death in situ of pericyte in the early stages of retinopathy, and with the advance of disease th e endothelial cell apoptosis occurs." @default.
- W2362595255 created "2016-06-24" @default.
- W2362595255 creator A5044137839 @default.
- W2362595255 date "2004-01-01" @default.
- W2362595255 modified "2023-09-23" @default.
- W2362595255 title "Experimental study on programmed retinal cell death in diabeticrats" @default.
- W2362595255 hasPublicationYear "2004" @default.
- W2362595255 type Work @default.
- W2362595255 sameAs 2362595255 @default.
- W2362595255 citedByCount "0" @default.
- W2362595255 crossrefType "journal-article" @default.
- W2362595255 hasAuthorship W2362595255A5044137839 @default.
- W2362595255 hasConcept C118487528 @default.
- W2362595255 hasConcept C123012128 @default.
- W2362595255 hasConcept C125473707 @default.
- W2362595255 hasConcept C126322002 @default.
- W2362595255 hasConcept C134018914 @default.
- W2362595255 hasConcept C142724271 @default.
- W2362595255 hasConcept C169760540 @default.
- W2362595255 hasConcept C190283241 @default.
- W2362595255 hasConcept C196795494 @default.
- W2362595255 hasConcept C202751555 @default.
- W2362595255 hasConcept C2777093970 @default.
- W2362595255 hasConcept C2778313320 @default.
- W2362595255 hasConcept C2779280383 @default.
- W2362595255 hasConcept C2779829184 @default.
- W2362595255 hasConcept C2780427682 @default.
- W2362595255 hasConcept C2780827179 @default.
- W2362595255 hasConcept C31573885 @default.
- W2362595255 hasConcept C55493867 @default.
- W2362595255 hasConcept C555293320 @default.
- W2362595255 hasConcept C71924100 @default.
- W2362595255 hasConcept C74864618 @default.
- W2362595255 hasConcept C75786782 @default.
- W2362595255 hasConcept C86803240 @default.
- W2362595255 hasConceptScore W2362595255C118487528 @default.
- W2362595255 hasConceptScore W2362595255C123012128 @default.
- W2362595255 hasConceptScore W2362595255C125473707 @default.
- W2362595255 hasConceptScore W2362595255C126322002 @default.
- W2362595255 hasConceptScore W2362595255C134018914 @default.
- W2362595255 hasConceptScore W2362595255C142724271 @default.
- W2362595255 hasConceptScore W2362595255C169760540 @default.
- W2362595255 hasConceptScore W2362595255C190283241 @default.
- W2362595255 hasConceptScore W2362595255C196795494 @default.
- W2362595255 hasConceptScore W2362595255C202751555 @default.
- W2362595255 hasConceptScore W2362595255C2777093970 @default.
- W2362595255 hasConceptScore W2362595255C2778313320 @default.
- W2362595255 hasConceptScore W2362595255C2779280383 @default.
- W2362595255 hasConceptScore W2362595255C2779829184 @default.
- W2362595255 hasConceptScore W2362595255C2780427682 @default.
- W2362595255 hasConceptScore W2362595255C2780827179 @default.
- W2362595255 hasConceptScore W2362595255C31573885 @default.
- W2362595255 hasConceptScore W2362595255C55493867 @default.
- W2362595255 hasConceptScore W2362595255C555293320 @default.
- W2362595255 hasConceptScore W2362595255C71924100 @default.
- W2362595255 hasConceptScore W2362595255C74864618 @default.
- W2362595255 hasConceptScore W2362595255C75786782 @default.
- W2362595255 hasConceptScore W2362595255C86803240 @default.
- W2362595255 hasLocation W23625952551 @default.
- W2362595255 hasOpenAccess W2362595255 @default.
- W2362595255 hasPrimaryLocation W23625952551 @default.
- W2362595255 hasRelatedWork W1975971009 @default.
- W2362595255 hasRelatedWork W1977781630 @default.
- W2362595255 hasRelatedWork W2025375706 @default.
- W2362595255 hasRelatedWork W2371342191 @default.
- W2362595255 hasRelatedWork W2385123668 @default.
- W2362595255 hasRelatedWork W2589594885 @default.
- W2362595255 hasRelatedWork W2898113033 @default.
- W2362595255 hasRelatedWork W2959232164 @default.
- W2362595255 hasRelatedWork W2998705497 @default.
- W2362595255 hasRelatedWork W3000529316 @default.
- W2362595255 hasRelatedWork W3029096683 @default.
- W2362595255 hasRelatedWork W3029393518 @default.
- W2362595255 hasRelatedWork W3029957996 @default.
- W2362595255 hasRelatedWork W3030045179 @default.
- W2362595255 hasRelatedWork W3031290628 @default.
- W2362595255 hasRelatedWork W3032474110 @default.
- W2362595255 hasRelatedWork W3032732757 @default.
- W2362595255 hasRelatedWork W3045025803 @default.
- W2362595255 hasRelatedWork W3143453249 @default.
- W2362595255 hasRelatedWork W3030755480 @default.
- W2362595255 isParatext "false" @default.
- W2362595255 isRetracted "false" @default.
- W2362595255 magId "2362595255" @default.
- W2362595255 workType "article" @default.