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- W2362680905 abstract "Objective Transverse myelitis (TM) is a rare but severe complication of systemic lupus erythematosus (SLE). We report 8 cases from our center. The clinical features, therapeutic methods, and prognosis of this entity are summarized. Methods One thousand, nine hundred and eigty-four SLE inpatients charts duration 1998—2005 were reviewed retrospectively. Eight cases of TM in SLE were identified. Descriptive analysis and literature review were performed. Results The median onset age of SLE of the eight patients (7 female and 1 male) was 19 years old (15~32 years of age). TM median occurrence time from onset of SLE was 8 months (0～12 years). Except one patient had cervical spinal cord involvement, all other 7 TM patients′ lesions were located at the thoracic region (T1～T9). MRI was of value to the diagnosis. Two patterns of lesions, longitudinal or speckle were identified. There was no other specific clinical features, including serology (only two patients had antiphospholipid antibodies) and cerebral spinal fluid analysis that could indicate the occurrence of TM. Four patients responded poorly and had severe neurological deficits remained. Three patients had recovered completely, who had received aggressive corticosteroid pulse therapy at the early stage (10 days) of the initiation of TM. One patient had a spontaneous remission tendency. Conclusion TM is a poorly understood complication of SLE, and prone to affect young patients in the early course of the disease. Thoracic spinal cord is the most frequently involved. There is no certain association of TM with antiphospholipid antibodies in our series. Prompt aggressive therapy may improve the outcome. Patients with muscle strength higher than grade Ⅲ may have a better prognosis." @default.
- W2362680905 created "2016-06-24" @default.
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- W2362680905 date "2006-01-01" @default.
- W2362680905 modified "2023-09-26" @default.
- W2362680905 title "Transverse myelitis in systemic lupus erythematosus" @default.
- W2362680905 hasPublicationYear "2006" @default.
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