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- W2362719640 abstract "To study the therapeutic efficacy of recombinant interferon alfa - 2a and alfa - 2b for the treatment of chronic hepatitis B 110 Chinese patients with chronic hepatitis B entered randomly into two groups. One group (52) was given IFNα- 2a 3 million u-nit(MU)/day. The control group (58) was given IFNa- 2b 3 million (3MU)/day. The changes of ALT, HBeAg and HBV DNA in the serum were observed and analyzed after three and six months later. On removing of HBeAg, The IFNa - 2b therapy group was(51.7% ,67.2% ) and the IFNα - 2a therapy group was (32.7% ,44.2%). On removing of HBV DNA, The IFNα - 2b therapy group was (58.6%) and the IFNα-2a therapy group was (34.6%) after 6 months later. The IFNα-2b therapy group efficacy was higher than The IFNα - 2a therapy group (P 0.05). The end treatment response of both HBeAg and HBV DNA, the IFNα-2b therapy group was (46.6%) and the IFNα- 2a therapy group was (21.2%). there was a significant difference between two groups ( P 0.01). The therapeutic efficacy of recombinant interferon alfa - 2b was better than the IFNα - 2a for the treatment of chronic hepatitis B." @default.
- W2362719640 created "2016-06-24" @default.
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- W2362719640 date "2003-01-01" @default.
- W2362719640 modified "2023-09-25" @default.
- W2362719640 title "The therapeutic efficacy of recombinant interferon alfa - 2a and alfa - 2b for the treatment of chronic hepatitis B" @default.
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