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- W2362719905 abstract "Objective This study was to determine the effective dose of remifentanil required to prevent double-lumen endobronchial intubation response in 50%of patients(ED50)anesthetized with propofol combined with magnesium sulfate and lidocaine cream.Methods Patients undergoing thoracotomy were enrolled in the study.BP,HR and ECG were continuously monitored and recorded before induction(baseline).Before induction,intravenous magnesium sulfate was given at 30 mg/kg then continuously infused at 15 mg·kg-1·h-1 until the completion of intubation.The lidocaine cream was applied in the catheter tip.Propofol 2.0 mg/kg,cisatracurium besilate 0.3 mg/kg and remifentanil were given successively to facilitate the intubation.ED50 was determined by up and down sequential trial.The ratio of two close dose was 1.2.Results The ED50 of remifentanil was 0.91μg/kg.The 95%confidence interval was 0.80-1.04μg/kg.Conclusion The ED50 of remifentanil for suppression of double-lumen endobronchial intubation response was 0.91μg/kg in patients anesthetized with propofol combined with magnesium sulfate and lidocaine cream." @default.
- W2362719905 created "2016-06-24" @default.
- W2362719905 creator A5013202736 @default.
- W2362719905 date "2015-01-01" @default.
- W2362719905 modified "2023-10-16" @default.
- W2362719905 title "Effect of intravenous magnesium sulfate combined with topical lidocaine cream on the ED_(50) of remifentanil for the suppression of the double-lumen endobronchial intubation response under propofol anesthesia" @default.
- W2362719905 hasPublicationYear "2015" @default.
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