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- W2362724373 abstract "Objective To study changes and clinical significance of plasma adiponectin and plasminogen activator inhibitor levels in patients with type 2 diabetes mellitus(T2DM)with coronary heart disease(CHD).Methods 105 T2DM patients and 50 health cases(NC) were enrolled.Furthermore,105 T2DM patients were divided into two subgroups:T2DM without CHD group(DM,n=50) and T2DM with CHD group(DC,n=50).Plasma concentration of adiponectin and PAI-1 were measured by emzyme-linked immunosorbent assay(ELISA).Results Plasma concentrations of adiponectin in T2DM patients were significantly lower than that of health cases(P0.05) and DC group were significantly lower than DM group(P0.05).However,Plasma concentrations of PAI-1 in T2DM patients were significantly higher than that of health cases(P0.05) and DC group were significantly higher than DM group(P0.05).Linear correlation analysis shows that there were negative correlation between the plasma concentration of adiponectin and PAI-1 and the coefficient was-0.463(P0.01).Conclusion Dropping of plasma adiponectin levels and increasing the activity of PAI-1 played an important role in arteriosclerosis in type 2 diabetes mellitus patients with coronary heart disease." @default.
- W2362724373 created "2016-06-24" @default.
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- W2362724373 date "2013-01-01" @default.
- W2362724373 modified "2023-09-26" @default.
- W2362724373 title "Investigation of the relationship between plasma adiponectin levels and fibrinolytic activities in patients with type 2 diabetes mellitus with coronary heart disease" @default.
- W2362724373 hasPublicationYear "2013" @default.
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