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- W2362751229 abstract "Objective To assess MRI value in differential diagnosis of hematological diseases. Methods MRI of bone marrow in lumber spine in 94 patients with pathologically proved hematological diseases, including 38 cases of acute leukemia, 20 cases of multiple myeloma, 8 cases of Med-anemia, 3 cases of mycelodysplastic syndrome, 16 cases of aplastic anemia, 3 cases of acute pure red cell aplasia, and 6 cases of myelofibrosis, was performed on a 0.5 T superconductive MR scanner. Abnormal MR signal intensity of bone marrow and vertebra destruction were studied with measurement of the T 1 relaxation value. Results Bone marrow showed homogenous low signal intensity on T 1WI and homogenous iso-signal intensity on T 2WI in 38 cases of acute leukemia and 8 cases of Med-anemia, and their T 1 values were increased without significant differences (P0.05). Homogenous or inhomogenous high signal in aplastic anemia were detected with decreased T 1 value. Homogenous iso-intensity was revealed in acute pure red cell aplasia with normal T 1 value. Aplastic anemia and acute pure red cell aplasia had a homogenous signal on T 2WI, their T 1 value showed significant difference (P0.01).Inhomogeneous low signal intensity on T 1WI and inhomogeneous high signal intensity on T 2WI were demonstrated with vertebra destruction in 75%(15/20) of multiple myeloma. Low homogenous signal intensity was showed on T 1 and T 2WI in myelofibrosis. Conclusion (1) Differential diagnosis can be made among acute leukemia, multiple myeloma, aplastic anemia, and myelofibrosis according to abnormal changes of MR signal intensity. (2) MRI was useful to distinguish between aplastic anemia and acute pure red cell aplasia, which were difficult to separate on clinic. (3) Some hematological diseases should still be analyzed with the combination of MRI and clinical information." @default.
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- W2362751229 date "2001-01-01" @default.
- W2362751229 modified "2023-09-23" @default.
- W2362751229 title "MRI value of differential diagnosis in hematological diseases (a report of 94 cases)" @default.
- W2362751229 hasPublicationYear "2001" @default.
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