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- W2362784060 abstract "Objective To observe the anti-tumor effect and explore the possible mechanism of Caoqi granule on tumor bearing mice.MethodsThe mice were transplanted by armpit injection of S180 tumor cells,and divided into positive control(5-FU),low dose group(Caoqi keli,2.21 g/kg),middle dose group(Caoqi keli,4.43 g/kg) and high dose group(Caoqi keli,8.85g/kg).Using immnunohistochemical staining technique,we detected the apoptotic related gene Bax,Bcl-6,Hsp27 protein expression.ResultsThe phenomena of a large of tumor cell death and apoptosis were observed.The death index of three therapy groups with Caoqi keli was 2.26(low)、2.50(middle) and 2.76(high),which was higher than that of the positive group(1.74).The expression of apoptotic related gene Bax,Bcl-6,Hsp27 were higher than that of model and positive group.ConclusionCaoqi granule can induce tumor cell death and apoptosis and inhibit the growth of S180 tumor cell line in vivo." @default.
- W2362784060 created "2016-06-24" @default.
- W2362784060 creator A5052713582 @default.
- W2362784060 date "2009-01-01" @default.
- W2362784060 modified "2023-09-23" @default.
- W2362784060 title "Study on the Tumor Inhibitory Effect of Caoqi Granule" @default.
- W2362784060 hasPublicationYear "2009" @default.
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