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- W2362804877 abstract "Shaking flask fermentation was carried out with Streptococcus zooepidemicus and effects of temperature in the range of 30℃ to 40℃ on hyaluronic acid(HA) production in batch fermentation was studied.The results showed that biomass of bacteria reached the highest at 34℃ and the highest dry cell weight was 13.1g/L,and the highest HA production occurred at 38℃,which was 82mg/100ml.A strategy of intermittent temperature control was proposed base on those experiments.And the optimum fermentation process was obtained by orthogonal test as follows: the temperature was kept at 34℃ for the first 12h,and then switched to 40℃ for 12h followed turn back to 34℃ and kept for 2h,the cycle was repeated until the end of the fermentation.Under this conditions,HA yield reached 105.30mg/100mL,which increased by 38.20% compared with constant temperature fermentation." @default.
- W2362804877 created "2016-06-24" @default.
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- W2362804877 date "2011-01-01" @default.
- W2362804877 modified "2023-09-24" @default.
- W2362804877 title "Control of intermittent temperature during hyaluronic acid batch fermentation" @default.
- W2362804877 hasPublicationYear "2011" @default.
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