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- W2362809655 abstract "Objective To study the expression of c-Met in breast cancer,and its response to neoadjuvant chemotherapy and prognosis.Methods Immunohistochemical staining of c-Met was performed by the standard streptavidin-peroxidase(SP) technique for the paraffin section of 147 breast cancers.The relationship between the c-Met expression and the clinicopathological parameters or the results of neoadjuvant chemotherapy were analyzed.The correlation between c-Met expression and the survival rate of patients,for whom long-term follow-up data were available,was investigated.Results The expression of c-Met in breast carcinoma tissues were significantly correlated with the histologic grade,lymph nodal metastasis and tumor staging(P0.05).It was related to neoadjuvant chemotherapy and patient survival.Conclusions The expression of c-Met in breast cancer was strongly associated with axillary lymph node metastasis and response to neoadjuvant chemotherapy.It could be used as a significant prognostic parameter of outcome in breast cancer." @default.
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- W2362809655 date "2011-01-01" @default.
- W2362809655 modified "2023-09-23" @default.
- W2362809655 title "Expression of c-Met and its clinical significance in breast cancer" @default.
- W2362809655 hasPublicationYear "2011" @default.
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