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- W2362828131 abstract "Objective: To investigate the clinical value of ion torrent sequencing with DNA for non-small cell peripheral lung cancer. Method: 80 cases were divided into two groups,each with 40 cases,the observation group were used three generations with ion torrent sequencing technology,the control group were used the first- generation sequencing technology method with Sanger sequencing,then sequencing proceeds before and after surgery and EGFR by ion torrent K- ras results and statistics sequencing EGFR- positive a two- year survival were compared. Result: The observation group with no surgery of EGFR- positive and K- ras mutation positive detection rate were significantly higher than those of control group( P 0. 05),theobservation group with recurrence of EGFR- positive group and K- ras mutations were significantly higher than those of control group( P 0. 05),1- year survival rate in the observation group was significantly higher than that of control group( P 0. 05). Conclusion: Ion torrent sequencing technology to measure peripheral blood DNA with non- small cell lung cancer patients can more accurately determine the genetic type of the patient,and thus provide the basis for molecular targeted therapy." @default.
- W2362828131 created "2016-06-24" @default.
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- W2362828131 date "2015-01-01" @default.
- W2362828131 modified "2023-09-26" @default.
- W2362828131 title "The Clinical Value of Ion Torrent Sequencing with DNA for Non- small Cell Peripheral Lung Cancer" @default.
- W2362828131 hasPublicationYear "2015" @default.
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