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- W2362851866 abstract "Objective:To observe the effect of continuous subcutaneous insulin infusion(CSII) on type 2 diabetic microangiopathy.Methods:A total of 80 patients with type 2 diabetic microangiopathy who received CSII intensive therapy for 4 weeks.The changes of serum inflammatory factors such as C-reaction protein(CRP).Hypersensitive C-reaction protein(hsCRP).Serum type Ⅳcollagen(CⅣ) and fibrinolytic factors(tissue-type plasminogen activator t-PA,tissue-type plasminogen activator inhibitor PAI-1) before and after treat-ment were compared.Results:CRP,hsCRP,serum CⅣand PAI-1 in patient with type 2 diabetic microangiopathy were significantly higher than those in normal control group(P0.01),while the level of t-PA was lower than that in normal control group(P0.01).After 4 weeks of CSII therapy,the levels of FBG and 2h-postprandial glucose obviously decreased(P0.01).And the level of HbAlc,insulin resistance in-dex(IRI),CRP,hsCRP and CⅣ all decreased(P0.05),and the level of PAI-1 significantly decreased(P0.01),while the level of t-PA obviously increased(P0.01).Conclusion:Type 2 diabetic microangiopathy is correlated with serum inflammatory factors,CⅣ and fibri-nolytic factors.CSII therapy not only can decrease the blood glucose,but also obviously reduce serum levels of inflammatory factor and CⅣ,and improve the function of fibrinolytic factors,and reduce insulin resistance." @default.
- W2362851866 created "2016-06-24" @default.
- W2362851866 creator A5070026931 @default.
- W2362851866 date "2013-01-01" @default.
- W2362851866 modified "2023-09-28" @default.
- W2362851866 title "Impact of Continuous Subcutaneous Insulin lnjection on Type 2 Diabetic Microangiopathy" @default.
- W2362851866 hasPublicationYear "2013" @default.
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