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- W2362877653 abstract "Objective: To study the apoptosis in peripheral blood lymphocytes (PBL) and the pathogenic mechanism of the Yin Jaundice rats. Method: The Yin Jaundice animal model were induced by combing a-nephthylisothiocynate (ANIT) with Deihuang, to demons trate the apoptosis in peripheral blood of rat by TUNEL standing method and deter-min the percentages of apoptosis in PBL of the Yin Jaundice rats by flow cytometer. In addition , the change of expressions in relates Bcl-2, Bcl-XL and Bax gene were observed by using immunohistochemical method. Result: Typical apop-totic cells were observed in the PBL of the Yin Jaundice rats and the percentage of apoptotic cells were significantly higher than those of normal,treated by herb and the Yang Jaundice rats. There was down-regulation in the expression of Bcl-2 and Bcl-XL in PBL of the Yin Jaundice, but the Bax expression remained obviously high. Conclusion: Apoptosis exists in the immunocytes of the Yin Jaundice rats. It is possible the reason that there are low immunity in the Yin Jaundice rats." @default.
- W2362877653 created "2016-06-24" @default.
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- W2362877653 date "2002-01-01" @default.
- W2362877653 modified "2023-09-23" @default.
- W2362877653 title "A Study of Apoptosis and Gene Regulation in Peripheral Blood Lymphocytes of Yin Jaundice" @default.
- W2362877653 hasPublicationYear "2002" @default.
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