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- W2362881415 abstract "AIM: To study the dose-effect relationship of beryl-lium sulfate (BeSO_4) on lymphocyte DNA damage in mice. METHODS: Spleen lymphocytes from mice were exposed to BeSO_4 at 0.2, 2, 20, 100, 200 μmol/L for 1 and 2 h, DNA damage of spleen lymphocytes were measured by the single-cell gel electrophoresis (SCGE). CASP software was used for analyzing the comet pictures including percentage tail DNA, tail length, tail moment and Olive tail moment. RESULTS: Significant differences were detected in the 5 groups as compared with the control group (P0.01); dose-response relationship was revealed. Differences between 1 h and 2 h groups at the same dose level were not significant. CONCLUSION: BeSO_4 could induce genotoxicity and DNA damage in mouse lymphocytes in vitro." @default.
- W2362881415 created "2016-06-24" @default.
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- W2362881415 date "2007-01-01" @default.
- W2362881415 modified "2023-09-23" @default.
- W2362881415 title "Dose-dependent effect of beryllium sulfate on DNA damage in mouse lymphocytes in vitro" @default.
- W2362881415 hasPublicationYear "2007" @default.
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