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- W2362884668 abstract "Objectives: To investigate the effect of sevoflurane or propofol-remifentanil anesthesia on effect-site concentration and neuromuscular blockade effects of atracurium by target-controlled infusion. Methods: Sixty patients were randomly allocated to group A propofol-remifentanil and group B sevoflurane anesthesia. The induced target effect-site concentration of atracurium was set at 2 μg·mL-1 and adjusted manually to maintain T1≤5% of the control height during operations. The following variables were recorded: target effect-site concentration, anesthesia time, total amount of atracurium, spontaneous recovery index, and the time interval from termination of TCI atracurium to recovery of TOFR to 0.9. Results: Effect-site concentration was degraded in both groups since 30 min after TCI of atracurium(P 0.05). The average dosage of atracurium and spontaneous recovery index was significant smaller in group B than in group A(P 0.05). Conclusion: Both sevoflurane and propofol-remifentanil anesthesia can reduce target effect -site concentration of atracurium by time dependence. Further, the recovery is faster in the sevoflurane anesthesia." @default.
- W2362884668 created "2016-06-24" @default.
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- W2362884668 date "2007-01-01" @default.
- W2362884668 modified "2023-09-28" @default.
- W2362884668 title "Neuromuscular Blockade of Atracurium by Target-controlled Infusion" @default.
- W2362884668 hasPublicationYear "2007" @default.
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