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- W2362949594 abstract "Objective: The purpose of this study was to explore effect of exercise eccentric on the imbalance of Th1/Th2 and the relationship between these and the cortisol(Cor),Interleukin-1β(IL-1β) and Interleukin-6(IL-6) by downhill frog-jump exercise fatigue model.Methods: The subjects performed 25×20 sets' downhill frog-jump on the 20 degrees' ramp under empty stomach.Each set frog-jump's distance was more than 45m and asked to perform it in 30s.Interval time between sets is 2min.Interferon-γ(IFN-γ),Interleukin-4(IL-4),Serum Concentration of Cor,IgG、 IgA、IgM,and T-lymphocyte transformation index(T-LTI) were detected before exercise and 0min,3h post exercise.Results: After exercise 0min and 3h,IFN-γ、ratio of IFN-γ/IL-4 and T-LTI decreased the level of 38%、36%、31%、31%、48% and 46% of that before exercise respectively,but IL-4 and Ig had not change significantly.While Cor,IL-1β,IL-6,increase significantly after exercise 0min,except IL-1β,the rest was not completely to recover to normal level after three hours rest.There were significantly positive correlation interaction between IFN-γ,IFN-γ/IL-4 and T-LTI(P0.01).There were significantly negative correlation between the IFN-γ/IL-4 and the Cor,IL-6,and between the IFN-γ and the Cor,IL-6,and between the Cor and the T-LTI,IgG,IgA,IgM,and bewteen IL-1β and the T-LTI,IgA,IgM,bewteen IL-6 and the T-LTI,IgA respectively(P0.05).IL-4 had not correlation with the rest index.Conclusion: It leads to Th1/Th2 toward Th2 excursion for exhaustive frog-jump exercise,which reduced the cellular immunity function.These changes were in relation with the elevated serum concentration of Cor、IL-1βand IL-6." @default.
- W2362949594 created "2016-06-24" @default.
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- W2362949594 date "2011-01-01" @default.
- W2362949594 modified "2023-09-26" @default.
- W2362949594 title "Effect of Downhill Frog-jump Exercise on the Imbalance of Th1/Th2 and the Relationship between These and the Cor,IL-1β and L-6" @default.
- W2362949594 hasPublicationYear "2011" @default.
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