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- W2362949841 abstract "Objective To evualate the effect of quercetin on inflammatory cytokines and oxidative stress in serum of cigarette smoke-exposed rats.Methods 20 SD rats were randomly divided into 4 groups: normal control group(group A),quercetin control group(group B),cigarette smoke –exposed group(group C),cigarette smoke + quercetin group(group D).Rats in group C and D revieved cigarette smoke exposure for 4 weeks and rats in group D were also treated with quercetin intraperitionally,Rats in group A were injected with saline and rats in group B were only treated with quercetin.4 weeks later,rats were sacrificed and TNF-α,IL-8,superoxide dismutase(SOD) activity,malondialdehyde(MDA) and total antioxidant capacity(T-AOC) in the serum of rats were examined.Results Cigarette smoke for 4 weeks increased the expression of TNF-α and IL-8,decreased SOD activity and T-AOC level and increased MDA level in the serum of rats,quercetin intervention improved such changes.Conclusion quercetin may decrease cigarette smoke-induced high inflmmatory cytokines expression and oxidative stress level in the serum of rats." @default.
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- W2362949841 date "2012-01-01" @default.
- W2362949841 modified "2023-09-26" @default.
- W2362949841 title "The effect of quercetin on serum inflammatory cytokines and oxidative stress in cigarette smoke-exposed rats" @default.
- W2362949841 hasPublicationYear "2012" @default.
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