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- W2362954488 abstract "Objective To investigate the effect of IL-10 on the proliferation of vascular smooth muscle A7r5 cells induced by AngⅡ and the expression of p53 and bcl-2.Methods The cell activity was assessed using MTT method.The cellular morphology was observed by inverted phase-contrast microscope.The expression of p53 and bcl-2 was detected by immunohistochemical method and western blot.Results IL-10 significantly inhibited A7r5 cell proliferation,but not in a dose-dependent manner,and reversed both p53 and bcl-2 expression.Conclusion IL-10 can prevent the vascular smooth muscle A7r5 cell proliferation induced by AngⅡ,which is related to modulation of the expression of p53 and bcl-2." @default.
- W2362954488 created "2016-06-24" @default.
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- W2362954488 date "2013-01-01" @default.
- W2362954488 modified "2023-09-23" @default.
- W2362954488 title "Inhibition of IL-10 in A7r5 cell proliferation induced by AngII" @default.
- W2362954488 hasPublicationYear "2013" @default.
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