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- W2362988439 abstract "Objective To explore the effect of theophylline on induced sputum interleukin-8(IL-8)and pulmonary functions in patients with stable chronic obstructive pulmonary disease(COPD).Methods 40 patients with stable COPD were divided into trial group(20 cases)and control group(20 cases)randomly.Trial group was treated with theophylline for 8 weeks,control group was given placebo for 8 weeks.Sputum IL-8 concentration and lung functions were determined at baseline and 8 weeks later.Results After 8 weeks of treatment,sputum IL-8 concentration in trial group dropped significantly(P0.05)and the indices of lung function improved significantly(P0.05).There were insignificant changes in the parameters in control group between baseline and 8 weeks later.Conclusion Theophylline can relieve airway inflammation,improve lung function in stable COPD patients." @default.
- W2362988439 created "2016-06-24" @default.
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- W2362988439 date "2011-01-01" @default.
- W2362988439 modified "2023-09-22" @default.
- W2362988439 title "Effect of theophylline on induced sputum interleukin-8 and pulmonary functions in patients with stable chronic obstructive pulmonary disease" @default.
- W2362988439 hasPublicationYear "2011" @default.
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