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- W2362991184 abstract "Rolling circle DNA amplification (RCA) is an isothermal signal amplification method.Phi 29 DNA polymerase can synthesize DNA strands70kbp in length and achieve a 10 5-fold linear and a 10 8-fold or more exponential amplification.The product produced by RAC can be linked to the primers or antibodies on the surface of solid phase(such as glass,microplate etc.) that make the RCA especially suitable for biochip research.As a new technique RCA is well suited to on-chip signal amplification that not only provide the sensibility and specificity of analysis but also keep the multiplexing of stereo-analysis.RCA is also a trace molecular detection method and will be exploited in research and detection of extremely trace biomacromolecule or biomarkers.;" @default.
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- W2362991184 date "2004-01-01" @default.
- W2362991184 modified "2023-10-09" @default.
- W2362991184 title "Principle and Application of Rolling Circle DNA Amplification" @default.
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