Matches in SemOpenAlex for { <https://semopenalex.org/work/W2363065711> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2363065711 abstract "Metformin has become a cornerstone in the treatment regime for type 2 diabetes mellitus because of its ability to control the amount of glucose in the blood.A series of studies have shown that it also confers greater cardiovascular protection than traditional antidiabetic agents.Other studies showed that there was a risk of heart failure(HF) due to metformin-associated lactic acidosis.More recent evidence,however,has shown no corresponding increase in the incidence of metformin-associated lactic acidosis.Indeed,studies have demonstrated that metformin may even reduce the risk of HF and mortality in diabetic patients.Its cardioprotective actions are connected to an increase of glucose transporter GLUT1 and GLUT4 production in heart cells,and inhibiting fatty acid oxidation.Importantly,the pleiotrophic actions of metformin are thought to be mediated by the activation of AMP-activated protein kinase(AMPK).Based on these findings,the cardioprotective nature of metformin has clinical implications and may encourage its widespread use in cardiovascular diseases." @default.
- W2363065711 created "2016-06-24" @default.
- W2363065711 creator A5050078795 @default.
- W2363065711 date "2012-01-01" @default.
- W2363065711 modified "2023-09-23" @default.
- W2363065711 title "Metformin and Heart Failure" @default.
- W2363065711 hasPublicationYear "2012" @default.
- W2363065711 type Work @default.
- W2363065711 sameAs 2363065711 @default.
- W2363065711 citedByCount "0" @default.
- W2363065711 crossrefType "journal-article" @default.
- W2363065711 hasAuthorship W2363065711A5050078795 @default.
- W2363065711 hasConcept C126322002 @default.
- W2363065711 hasConcept C134018914 @default.
- W2363065711 hasConcept C161573976 @default.
- W2363065711 hasConcept C164705383 @default.
- W2363065711 hasConcept C184235292 @default.
- W2363065711 hasConcept C185592680 @default.
- W2363065711 hasConcept C2776188179 @default.
- W2363065711 hasConcept C2777180221 @default.
- W2363065711 hasConcept C2777391703 @default.
- W2363065711 hasConcept C2777952866 @default.
- W2363065711 hasConcept C2778198053 @default.
- W2363065711 hasConcept C2779306644 @default.
- W2363065711 hasConcept C2780124434 @default.
- W2363065711 hasConcept C2780317664 @default.
- W2363065711 hasConcept C2780323712 @default.
- W2363065711 hasConcept C55493867 @default.
- W2363065711 hasConcept C555293320 @default.
- W2363065711 hasConcept C71924100 @default.
- W2363065711 hasConcept C97029542 @default.
- W2363065711 hasConcept C98274493 @default.
- W2363065711 hasConceptScore W2363065711C126322002 @default.
- W2363065711 hasConceptScore W2363065711C134018914 @default.
- W2363065711 hasConceptScore W2363065711C161573976 @default.
- W2363065711 hasConceptScore W2363065711C164705383 @default.
- W2363065711 hasConceptScore W2363065711C184235292 @default.
- W2363065711 hasConceptScore W2363065711C185592680 @default.
- W2363065711 hasConceptScore W2363065711C2776188179 @default.
- W2363065711 hasConceptScore W2363065711C2777180221 @default.
- W2363065711 hasConceptScore W2363065711C2777391703 @default.
- W2363065711 hasConceptScore W2363065711C2777952866 @default.
- W2363065711 hasConceptScore W2363065711C2778198053 @default.
- W2363065711 hasConceptScore W2363065711C2779306644 @default.
- W2363065711 hasConceptScore W2363065711C2780124434 @default.
- W2363065711 hasConceptScore W2363065711C2780317664 @default.
- W2363065711 hasConceptScore W2363065711C2780323712 @default.
- W2363065711 hasConceptScore W2363065711C55493867 @default.
- W2363065711 hasConceptScore W2363065711C555293320 @default.
- W2363065711 hasConceptScore W2363065711C71924100 @default.
- W2363065711 hasConceptScore W2363065711C97029542 @default.
- W2363065711 hasConceptScore W2363065711C98274493 @default.
- W2363065711 hasLocation W23630657111 @default.
- W2363065711 hasOpenAccess W2363065711 @default.
- W2363065711 hasPrimaryLocation W23630657111 @default.
- W2363065711 hasRelatedWork W1961192788 @default.
- W2363065711 hasRelatedWork W1966605117 @default.
- W2363065711 hasRelatedWork W1989287217 @default.
- W2363065711 hasRelatedWork W2001497361 @default.
- W2363065711 hasRelatedWork W2016089624 @default.
- W2363065711 hasRelatedWork W2022182182 @default.
- W2363065711 hasRelatedWork W2035838062 @default.
- W2363065711 hasRelatedWork W2073509884 @default.
- W2363065711 hasRelatedWork W2088488831 @default.
- W2363065711 hasRelatedWork W2255457724 @default.
- W2363065711 hasRelatedWork W2326596787 @default.
- W2363065711 hasRelatedWork W2382018013 @default.
- W2363065711 hasRelatedWork W2391680572 @default.
- W2363065711 hasRelatedWork W2747491011 @default.
- W2363065711 hasRelatedWork W2790119520 @default.
- W2363065711 hasRelatedWork W2810545965 @default.
- W2363065711 hasRelatedWork W2910786996 @default.
- W2363065711 hasRelatedWork W3128078423 @default.
- W2363065711 hasRelatedWork W2148637270 @default.
- W2363065711 hasRelatedWork W2739708854 @default.
- W2363065711 isParatext "false" @default.
- W2363065711 isRetracted "false" @default.
- W2363065711 magId "2363065711" @default.
- W2363065711 workType "article" @default.