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- W2363152009 abstract "Objective To investigate the level of serum retinol binding protein 4(RBP4) in patients with nonalcoholic fatty liver disease(NAFLD) and its relationship with obesity,insulin sensitivity,blood glucose,and blood lipid.Methods 64 patients with nonalcoholic fatty liver disease(NAFLD group) and 35 normal subjects(normal control group) were selected.The level of serum RBP4 was measured by ELISA.Height,weight,waist circumstance,hip girth,fasting blood glucose(FBG),blood lipid(TC,TG,HDL-C,LDL-C),liver function(AST,ALT),and fasting insulin(FINS) were measured.Body mass index(BMI),waist to hip ratio(WHR),homeostasis model assessment of insulin resistance(HOMA-IR)were calculated as well.Results Serum levels of FBG,TC,TG,LDL-C,FINS,RBP4 and HOMA-IR,BMI,WHR were higher in NAFLD patients as compared to normal controls(P0.01).And the moderate NAFLD group had higher FBG,TC,TG,LDL-C,FINS,RBP4 and HOMA-IR,BMI,WHR as compared with the mild NAFLD group(P0.01).Serum RBP4 were positively correlated with BMI,WHR,FBG,TC,TG,LDL-C,FINS and HOMA-IR(r=0.379,0.341,0.367,0.359,0.366,0.342,0.338,0.447,P0.01).Conclusion Serum RBP4 was involved in the insulin resistance during the development of nonalcoholic fatty liver disease." @default.
- W2363152009 created "2016-06-24" @default.
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- W2363152009 date "2011-01-01" @default.
- W2363152009 modified "2023-09-24" @default.
- W2363152009 title "Relationship between the Serum Retinol Binding Protein 4 and Insulin Resistance in Nonalcoholic Fatty Liver Disease" @default.
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