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- W2363163964 abstract "Objective:To evaluate the risk factors of serious nephronia evolved from microalbuminuria in the patients with Type 2 Diabetes.Methods:114 patients with type 2 Diabetes were selected randomly and were divided into 4 groups according to Urinary Albumin/Creatinine(UAlb/Cr),77 healthy subjects were selected as control group.UAlb/Cr was determined via immunoturbidimetry,Intimal medial thickness of the carotid artery(IMT) was measured by color Doppler with high resolution,Glomerular filtration rate(GFR) was calculated by simplified MDRD equations.Data from each group was statistically analyzed.Results:HbA1c and systolic blood pressure(SBP) were independent risk factors in the period of microalbuminuria after adjusting age,duration.Exp(B) were 1.028(95%CI 1.009-1.047,P=0.004)、1.314(95%CI 1.102-1.567,P=0.002)respectively.SBP,postprandial glucose(PPG) total1 cholesterol(TC) 、GFR and IMT were independent risk factors of UAlb/Cr in the period of clinical albuminuria,Exp(B) were 1.057(1.017-1.099,P=0.005),1.228(95%CI 1.027-1.469,P=0.024),2.666(95%CI 1.296-5.485,P=0.008),0.95(95%CI 0.932-0.978,P=0.00),22.703(95%CI 2.199-234.35,P=0.009)respectively.Conclusion:IMT is a extremely strong risk factor in promoting the evolvement of nephropathy in Type 2 Diabetes.Thickened IMT is a key factor in the development of microalbuminuria to clinical albuminuria." @default.
- W2363163964 created "2016-06-24" @default.
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- W2363163964 date "2009-01-01" @default.
- W2363163964 modified "2023-09-23" @default.
- W2363163964 title "Analysis of the Risk Factors of Serious Nephronia Evolved from Microalbuminuria in the Patients with Type 2 Diabetes Mellitus" @default.
- W2363163964 hasPublicationYear "2009" @default.
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