Matches in SemOpenAlex for { <https://semopenalex.org/work/W2363165933> ?p ?o ?g. }
- W2363165933 endingPage "351" @default.
- W2363165933 startingPage "341" @default.
- W2363165933 abstract "Sympathetic nervous system activation and catecholamine release are important events following injury and infection. The nature and timing of different pathophysiologic insults have significant effects on adrenergic pathways, inflammatory mediators, and the host response. Beta adrenergic receptor blockers (β-blockers) are commonly used for treatment of cardiovascular disease, and recent data suggests that the metabolic and immunomodulatory effects of β-blockers can expand their use. β-blocker therapy can reduce sympathetic activation and hypermetabolism as well as modify glucose homeostasis and cytokine expression. It is the purpose of this review to examine either the biologic basis for proposed mechanisms or to describe current available clinical evidence for the use of β-blockers in traumatic brain injury, spinal cord injury, hemorrhagic shock, acute traumatic coagulopathy, erythropoietic dysfunction, metabolic dysfunction, pulmonary dysfunction, burns, immunomodulation, and sepsis." @default.
- W2363165933 created "2016-06-24" @default.
- W2363165933 creator A5005967890 @default.
- W2363165933 creator A5031214939 @default.
- W2363165933 creator A5046193991 @default.
- W2363165933 creator A5081164839 @default.
- W2363165933 date "2016-10-01" @default.
- W2363165933 modified "2023-10-18" @default.
- W2363165933 title "β-Blockade use for Traumatic Injuries and Immunomodulation" @default.
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