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- W2363179092 abstract "Objective Observe the clinic curative effect and the security to earlier suffierers from acute-on-chronic liver failure and chroic liver failure through using the treatment with lamivudinr or entecavir combining with glucocorticoid.Methods 76 cases were randomly divided into two groups,both of whom are treated with comprehensive and antiviral therapy while being peroraled prednisone,and then observe the clinic situation and cure rate of those sufferers while testing biochemical indicator,PTA and bloodserum HBV DNA capacity ending with the period of 12 weeks.Results The group with treatment obviously got better after one week's treatment while the one without treatment almost kept the same as before with half got worse.Comparing the situation among the forth week,8 weeks and 12 weeks,we found that ALT,TBIL,TC amd PTA are greatly improved with obvious differences(P≤0.01).Comparing the group with treatment with the one without treatment in different period of 4 weeks,8 weeks,and 12 weeks,we found that all index of the former is greatly improved with obvious differences(P≤0.05).In the 4th and 12th week,comparing the serum HBV DNA rate between the two groups,we did not find statistics significance from the cooperation.(P0.05).After 12 weeks,all HBV DNA turned darkening(500 copies/ml).Comparing with the other group,the group with treatment had cure rate of 82.5%(33/40),higher than the other group of 61.1%(22/36),with obvious differences(P0.05) and without untoward effect during the treatment.What's more,in the group with treatment,the incidence rate of hepatic encephalopathy,hepatorenal syndrome is greatly lower than that in the other group.Conclusion The survival rate and safety are greatly improved through early treating sufferets from acute-on-chronic liver failure and chronic liver failure with lamivudine or entecavir combining with glucoconicoid." @default.
- W2363179092 created "2016-06-24" @default.
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- W2363179092 date "2012-01-01" @default.
- W2363179092 modified "2023-09-24" @default.
- W2363179092 title "Clinic Observation to the Treatment of Hypohepatia with Antiviral Combining with Glucocorticoid" @default.
- W2363179092 hasPublicationYear "2012" @default.
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