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- W2363275665 abstract "Objective To study the inhibitory effects and mechanism of HB on the growth of Hep 2 cell.Methods Observing HB inhibitory effect on the growth of Hep 2 cell with MTT assay. Laser scanning confocal microscope was applied to study cell intracellular calcium and the concentration of DNA in cell.Results After Hep 2 cell had been treated with HB(10μg/ml,100μg/ml )for 72h,the survival rate decreased obviously.Its DNA concentration decreased significantly after had been treated with 10 or 20μg/ml HB for 48h( P 0.001 ).On the contrary, cell intracellular calcium increased obviously( P 0.001).Conclusion HB could inhibit the growth of Hep 2 cell which is related to decreasing DNA concentration or overloading of calcium in cell." @default.
- W2363275665 created "2016-06-24" @default.
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- W2363275665 date "2001-01-01" @default.
- W2363275665 modified "2023-09-26" @default.
- W2363275665 title "Mechanism research of inhibitory effect of a traditional Chinese drug HB on the growth of Hep-2 cell" @default.
- W2363275665 hasPublicationYear "2001" @default.
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