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- W2363278364 abstract "【Objective】 To investigate the alteration of Th17 cells and CD4+ CD25+ CD127-regulatory T cells(Treg) in patients with end-stage kidney disease(ESKD).【Methods】 The frequencies of Th17 and Treg cells in 21 patients on uraemic patients(uremia group),21 renal allograft recipients(renal allograft group) and 21 healthy blood donors(normal control group) were detected by flow cytometry.【Results】 Frequencies of Th17 cells were significantly lower in uremia group and renal allograft group than the healthy controls(P 0.05,P 0.01),and frequencies of Treg cells were significantly lower in uremia group and renal allograft group than the healthy controls(P 0.01,P 0.01).It was confirmed that the ratios of Th17/Treg increased in uremia group(P 0.05).【Conclusion】 Th17/Treg imbalance exists in patients with uremia,so it may play a potential role in the immunity and lead to occur and development of uremia." @default.
- W2363278364 created "2016-06-24" @default.
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- W2363278364 date "2011-01-01" @default.
- W2363278364 modified "2023-09-23" @default.
- W2363278364 title "Frequency and balance of Th17 and Treg cells in patients with end-stage kidney disease" @default.
- W2363278364 hasPublicationYear "2011" @default.
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