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- W2363300512 abstract "Objective To investigate the anti-Coxsackie virus B3 (CVB3) effect of artemisinin in vitro. Method The anti-CVB3 effect of artemisinin was detected by micro cytopathogenic effect inhibition assay in vitro. Moreover, semi-quantitive RT-PCR and indirect immunofluorescence assay were used to investigate the inhibitive effect of artemisinin on CVB3 RNA replication and protein expression. Results Artemisinin had inhibition on CVB3 adherence and replication to different extents according to the ever increasing drug concentration. Artemisinin(15.0 μg/ml) efficiently inhibited CVB3 RNA replication and protein expression. Direct virucidal activity of artemisinin was not found. Conclusions Artemisinin plays an important role in the anti-CVB3 effect in vitro by means of inhibiting CVB3 from adhering to the host cells and replicating in them." @default.
- W2363300512 created "2016-06-24" @default.
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- W2363300512 date "2004-01-01" @default.
- W2363300512 modified "2023-09-25" @default.
- W2363300512 title "Study on anti-Coxsackie virus B3 effect of artemisinin" @default.
- W2363300512 hasPublicationYear "2004" @default.
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