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- W2363322929 abstract "Objective To explore the possible causes of MBP inducing EAE.Methods By acid abstraction and CM Sephadex50 chromatography purifying MBP and observe the pathogenicity EAE induced by MBP,with bio active assay to test TNF and IFN activity in the supernatant of PBMC stimulation.Results MBP identified by SDS PAGE was a single band .Which showed the activity of pathogenicity of EAE.The PBMC stimulated by MBP could produce TNF and IFN.Conclusions MBP may induce EAE by stimulating PBMC to produce proinflammatory cytokines TNF and IFN in periphery." @default.
- W2363322929 created "2016-06-24" @default.
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- W2363322929 date "2001-01-01" @default.
- W2363322929 modified "2023-09-25" @default.
- W2363322929 title "The Purification of Myelin Basic Protein and Its Effect on PBMC Producing TNF and IFN" @default.
- W2363322929 hasPublicationYear "2001" @default.
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