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- W2363361811 abstract "Objective To assess the clinical value of antithrombin(AT)for hematological malignancy patients.Methods 195 hematological malignancy patients were divided into newly-diagnosed group,complete remission(CR)group,partial remission(PR)group and progression of disease(PD)group.Clinical data of AT were analyzed retrospectivly for these groups and normal control group.Levels of AT,β2-microglobulin(β2-MG)and lactate dehydrogenase(LDH)were analyzed for multiple myeloma patients.Results The plasma AT activity of of newly-diagnosed group,CR,PR and PD group were lower than control group(P﹤0.01).Compared with CR group,AT of newly-diagnosed group,PR and PD group were decreased(P﹤0.01).For multiple myeloma patients,AT of PD,PR group become lower than CR group(P﹤0.05),but β2-MG of these groups were higher than CR group(P﹤0.05).There was negative correlation between AT and β2-MG(P﹤0.05).Conclusions The determination of levels of AT in patients with hematological malignancy might be important for the evaluation of the effect of treatment and prognosis." @default.
- W2363361811 created "2016-06-24" @default.
- W2363361811 creator A5013583966 @default.
- W2363361811 date "2010-01-01" @default.
- W2363361811 modified "2023-09-25" @default.
- W2363361811 title "Changes of Plasma Antithrombin Levels in Patients with Hematological Malignancy" @default.
- W2363361811 hasPublicationYear "2010" @default.
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