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- W2363385954 abstract "To investigate the therapeutic efficacy of administrating different dosage of recombinant lysostaphin(rLysostaphin) for bovine mastitis during lactation,104 udder quarters selected from 85 cows of mastitis were randomly assigned to 4 groups.Each group included 26 udder quarters.Three treatment groups(Group I,Group II and Group III) were treated with intramammary rLysostaphin infusion of low,middle and high dosage twice daily for 4 days.The low,middle and high dosage were 200,400 and 800 U rLysostaphinper per udder quarter respectively.The last group was treated with intramammary penicillin G sodium infusion(Group IV:1600000 IU/udder quarter of penicillin G sodium) as control.The results showed that the low,middle and high dosage of rLysostaphin effectively eradicated gram-positive pathogens such as Streptococci,Staphylococcus and Arcanobacterium pyogenes from infected udder quarters,decreased somatic cell count of milk secreted from infected udder quarters and increased daily milk yield.The effective rate and cure rate of low dosage(Group I) was higher than that of control group(P0.05).The effective rate and cure rate of middle and high dosage(Group II and Group III) was significantly higher than that of control group(P0.05).The therapeutic effect of Group II and Group III was comparative(P0.05).In conclusion,the rLysostaphin showed its high efficacy in the treatment of bovine mastitis caused by Staphylococcus and Streptococcus." @default.
- W2363385954 created "2016-06-24" @default.
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- W2363385954 date "2011-01-01" @default.
- W2363385954 modified "2023-09-26" @default.
- W2363385954 title "Therapeutic Efficacy of Recombinant Lysostaphin on Bovine Mastitis" @default.
- W2363385954 hasPublicationYear "2011" @default.
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