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- W2363407624 abstract "Objective:To investigate the depressant effects of Sorafenib on human liver cancer cell line HepG2 cells in vitro.Methods:MTT method was used to detect the antiproliferative ratio of Sorafenib on HepG2 cells,flow cytometry to analyze the cell cycle and apoptotic ratio.Results:Sorafenib could obviously inhibit proliferation of HepG2 cells and appeared time-dose-dependent effects.72 hours after the HepG2 cells were treated with Sorafenib in 6μmol/L,the percentage of HepG2 cells in S period increased,G0-G1 period and G2-M period HepG2 cells decreased,aopototic ratio of HepG2 cells increased significantly(P0.05,P0.01) .Conclusions:Sorafenib can inhibit proliferation and promote apoptosis of human liver cancer cell line HepG2 cells in vitro." @default.
- W2363407624 created "2016-06-24" @default.
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- W2363407624 date "2009-01-01" @default.
- W2363407624 modified "2023-09-24" @default.
- W2363407624 title "DEPRESSANT EFFECTS OF SORAFENIB ON HUMAN LIVER CANCER CELL LINE HEPG2" @default.
- W2363407624 hasPublicationYear "2009" @default.
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