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- W2363431293 abstract "Objective To explore the skills and characteristics of corneal neovascular model in rat induced by micropockct assay.Methods Nine eyes of nine Sprague-Dawley rats were studied.Pellets made of VEGF,poly-2-hydruxylethylmethacry- late and sucralfate were implanted into the corneal stroma no closer than 1 mm from the limbus.Biomicroscopic features of cor- neal neovnscular were observed on 1,3,5,7 day after the implantation.Results The First day after operation,the limbal vessels were dilated,with no angiogenesis appeared.The Third day,angiogenesis began to invade peri-cornea with a brush shape,the area of CNV was(2.23±0.59)mm~2.The Fifth day,new vessels reached the lower margin of pellet densely,the area of CNV was(6.81±1.35)mm~2.The Seventh day,new vessels continued to elongate,parts of them extended as loops toward the pellet,the area of CNV was(8.92±1.79)mm~2.Neither hyphema or other complications was occurred.Conclu- sion Corneal neovascular induced by micropocket assay in rat grows steadily,with no complication,and is suitable for quanti- tative researches." @default.
- W2363431293 created "2016-06-24" @default.
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- W2363431293 date "2007-01-01" @default.
- W2363431293 modified "2023-09-25" @default.
- W2363431293 title "Study on the Rat Models of Corneal Neovascularization Induced by Micropocket Assay" @default.
- W2363431293 hasPublicationYear "2007" @default.
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