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- W2363457036 abstract "Objective To investigate the effect of puerarin(Pue) on plasma TNF-α,leptin(Lep) and blood fat on the experimental insulin resistance (IR) rats induced by high fatty diet. For discuss the mechanism of puerarin improving IR. Methods Small dosage STZ was injected (iv) and high fatty diet was taken for 45 days,the rats with abnomal sugar tolerance were selected as IR rat models. The effect of Pue on insulin sensitivity was studied in IR rats which were treated with Pue for 60 days and the concentration of blood sugar,triglyceride(TG),total cholesterol (TC),insulin,TNF-α and Lep in plasma were detected. Results Pue could lower blood sugar and blood fat (TG,TC). At the same time the con-centration of plasma insulin,TNF-α and Lep in IR rats decreased,too. Conclusion Pue can increase insulin sensitivity of the experimental IR rats by decreasing TG,TC,TNF-α,Lep." @default.
- W2363457036 created "2016-06-24" @default.
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- W2363457036 date "2009-01-01" @default.
- W2363457036 modified "2023-09-23" @default.
- W2363457036 title "Influence of Puerarin on Plasma TNF-α,Leptin and Blood Fat on Insulin Resistance Rats Induced by High Fatty Diet" @default.
- W2363457036 hasPublicationYear "2009" @default.
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