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- W2363460218 abstract "In this paper,the effect of the Garlic polysaccharide(GAP) on SOD and MDA on concanavalin A(ConA)-induced liver injury in mice was investigated.50 mice were randomly divided into 5 groups: group 1(mice without any treatment set up as control group),group 2(mice intravenously injected with ConA only),group 3(mice treated with 100 mg/kg of GAP first,and then intravenously injected with ConA),group 4(mice treated with 200 mg/kg of GAP first,and then intravenously injected with ConA),group 5(mice treated with 400 mg/kg of GAP first,and then intravenously injected with ConA).After the liver injury was induced by intravenously injected ConA,the liver was removed.The activity of SOD and GSH,the content of MDA in liver tissue were determined.The result,compared with the model group,the activity of SOD and GSH had increased but the difference was not significant(P0.05),MDA was significantly lower(P0.05) in 100mg /kg GAP treated group(group 3);the activity of SOD and GSH increased significantly(P0.05),the content of MDA reduced significantly(P0.01) in 200 mg/kg GAP treated group(group 4);the activity of SOD and GSH increased significantly(P0.01),and the content of MDA was significantly lower(P0.001) in 400 mg/kg GAP treated group(group 5).It was showed that GAP could effectively improve the immune function and made a protective effect on liver damaged by ConA,and the protection is dose dependent in a certein range." @default.
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- W2363460218 date "2011-01-01" @default.
- W2363460218 modified "2023-09-22" @default.
- W2363460218 title "Effect of the GAP on SOD and MDA on liver injury induced by ConA in mice" @default.
- W2363460218 hasPublicationYear "2011" @default.
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