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- W2363511265 abstract "Objective To provide data for perfect selection of glutamic acid decarboxylase antibod- ies (GAD-Ab) assay commercial kits.Methods The sera of 88 titer-graded samples by radioligand assay (RLA) were measured with two types of enzyme-linked immunosorbent assay (ELISA) kits and one type of immunoradiometric assay (IRMA) kit tor GAD-Ab in order to test their consistency with RLA.Another 140 diabetic sera were measured with RIA and screened by a type of suitable kit to search the cutoff point for discriminating patients who needed rechecking.Results Compared with RLA,concordance ratio of 3 kits: Medizym kit(75%)RSR kit (73.9%)Biomerica kit (62.5%);Kappa value:Medizym kit (0.408, common)RSR kit (0.405,common)Biomerica kit (0.185,thiling);correlation to RLA index:RSR kit (r= 0,992)Medizym kit(r=0.791)Biomerica kit (r=-0.055);area under the receiver operating charac- teristic (ROC) curve:Medizym kit(0.812)RSR kit(0.727)Biomerica kit (0.666).Conclusions The efficiencies of RSR kit and Medizym kit are good.Serum concentration between 0.25～0.99 U/ml measured by RSR kit is suggested to further recheck by RLA." @default.
- W2363511265 created "2016-06-24" @default.
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- W2363511265 date "2006-01-01" @default.
- W2363511265 modified "2023-09-24" @default.
- W2363511265 title "A comparative study in three commercial kits of radioligand assay for GAD-Ab" @default.
- W2363511265 hasPublicationYear "2006" @default.
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