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- W2363513054 abstract "PurposeTo purify a kind of exotoxin (PAP) from the culture supernatant of Pseudomonas aeruginosa (ATCC 27853) and investigate the effects of PAP on the human hepatic cancer cell line SMMC-7721 and leukemic cell line K562.MethodsPAP was purified by ammonium persulfate precipitation, ultrafiltration and column chromatography. Molecular weight of PAP was determined by SDS-electrophoresis. The inhibition of SMMC-7721 and K562 cells by PAP were detected by MTT methods. ResultsThe molecular weight of PAP is 52 600. It inhibited the growth of SMMC-7721 and K562 cells (P0.01).ConclusionPAP has the antitumor ability." @default.
- W2363513054 created "2016-06-24" @default.
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- W2363513054 date "2004-01-01" @default.
- W2363513054 modified "2023-09-25" @default.
- W2363513054 title "Purification and antineoplastic effect of a kind of exotoxin secreted from Pseudomonas aeruginosa" @default.
- W2363513054 hasPublicationYear "2004" @default.
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