Matches in SemOpenAlex for { <https://semopenalex.org/work/W2363589996> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W2363589996 abstract "Objective To explore the expression of syndecan-1(Sdc-1)in dextran sodium sulphate(DSS)-induced mice colitis model,and to investigate the role of sdc-1 in mice colitis.Methods 54 C57BL/6 mice were divided into control group and DSS group.In model group,mice were fed with 5 % DSS solution ad libitum for 10 days to induce an acute colitis model.In the control group,mice were only fed with distilled water.The mice were killed separately on the 4th,7th and 10th day.Then the colonic histologic changes were observed and scored by light microscopy,and the expression of syndecan-1 in colonic tissues at mRNA and protein levels was respectively determined by reverse transcriptase polymerasechain reaction(RT-PCR) and immunohistochemistry.Results The histological score in model groups was significantly higher than that in control group(p0.01),and the highest score was on the 7th day(3.05±1.65)after colitis model construction.Both the expression of colonic Sdc-1 mRNA and sdc-1 protein in model group were all significantly lower than that in control group(p0.01),and the lowest score was on the 7th day,respectively.Conclusions The severity of colitis was relevant to the reduction of Sdc-1 protein level and Sdc-1 mRNA level of mice colon.Sdc-1 might be used as a marker for the diagnosis,treatment and disease monitoring of colitis." @default.
- W2363589996 created "2016-06-24" @default.
- W2363589996 creator A5034843029 @default.
- W2363589996 date "2009-01-01" @default.
- W2363589996 modified "2023-09-22" @default.
- W2363589996 title "Expression of Syndecan-1 in Mice Colitis Model that Acute Colitis Induced with DSS" @default.
- W2363589996 hasPublicationYear "2009" @default.
- W2363589996 type Work @default.
- W2363589996 sameAs 2363589996 @default.
- W2363589996 citedByCount "0" @default.
- W2363589996 crossrefType "journal-article" @default.
- W2363589996 hasAuthorship W2363589996A5034843029 @default.
- W2363589996 hasConcept C104317684 @default.
- W2363589996 hasConcept C105580179 @default.
- W2363589996 hasConcept C126322002 @default.
- W2363589996 hasConcept C1491633281 @default.
- W2363589996 hasConcept C185592680 @default.
- W2363589996 hasConcept C203014093 @default.
- W2363589996 hasConcept C204232928 @default.
- W2363589996 hasConcept C2775862500 @default.
- W2363589996 hasConcept C55493867 @default.
- W2363589996 hasConcept C65001120 @default.
- W2363589996 hasConcept C71924100 @default.
- W2363589996 hasConcept C90924648 @default.
- W2363589996 hasConceptScore W2363589996C104317684 @default.
- W2363589996 hasConceptScore W2363589996C105580179 @default.
- W2363589996 hasConceptScore W2363589996C126322002 @default.
- W2363589996 hasConceptScore W2363589996C1491633281 @default.
- W2363589996 hasConceptScore W2363589996C185592680 @default.
- W2363589996 hasConceptScore W2363589996C203014093 @default.
- W2363589996 hasConceptScore W2363589996C204232928 @default.
- W2363589996 hasConceptScore W2363589996C2775862500 @default.
- W2363589996 hasConceptScore W2363589996C55493867 @default.
- W2363589996 hasConceptScore W2363589996C65001120 @default.
- W2363589996 hasConceptScore W2363589996C71924100 @default.
- W2363589996 hasConceptScore W2363589996C90924648 @default.
- W2363589996 hasOpenAccess W2363589996 @default.
- W2363589996 hasRelatedWork W1514908668 @default.
- W2363589996 hasRelatedWork W1974419448 @default.
- W2363589996 hasRelatedWork W2349738648 @default.
- W2363589996 hasRelatedWork W2350876270 @default.
- W2363589996 hasRelatedWork W2352904100 @default.
- W2363589996 hasRelatedWork W2361178449 @default.
- W2363589996 hasRelatedWork W2362202708 @default.
- W2363589996 hasRelatedWork W2362346702 @default.
- W2363589996 hasRelatedWork W2367191191 @default.
- W2363589996 hasRelatedWork W2369299763 @default.
- W2363589996 hasRelatedWork W2383373361 @default.
- W2363589996 hasRelatedWork W2383732625 @default.
- W2363589996 hasRelatedWork W2385292273 @default.
- W2363589996 hasRelatedWork W2385712268 @default.
- W2363589996 hasRelatedWork W2387815549 @default.
- W2363589996 hasRelatedWork W2391132605 @default.
- W2363589996 hasRelatedWork W2394415661 @default.
- W2363589996 hasRelatedWork W2466923592 @default.
- W2363589996 hasRelatedWork W3028805286 @default.
- W2363589996 hasRelatedWork W3029298002 @default.
- W2363589996 isParatext "false" @default.
- W2363589996 isRetracted "false" @default.
- W2363589996 magId "2363589996" @default.
- W2363589996 workType "article" @default.