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- W2363646904 abstract "Alzheimer disease(AD),a progressive neurodegeneration disorder,is the most common type of dementia.Tau hyperphosphorylation is considered to be one of the central event in the pathogenesis of AD.Tau protein is a brain microtubule-associated protein that could be modified by protein kinases(phosphorylation)and protein phosphatase(dephosphorylation).The function abnormalities of tau protein may be a necessary part of the neuronal dysfunction and death.Here is to make a review focusing on the structure and function of tau,tau hyperphosphorylation,the accommodation of tau phosphorylation and the relationship between β-amyloid protein,tau protein and AD." @default.
- W2363646904 created "2016-06-24" @default.
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- W2363646904 date "2013-01-01" @default.
- W2363646904 modified "2023-09-25" @default.
- W2363646904 title "Tau Hyperphosphorylation and Alzheimer Disease" @default.
- W2363646904 hasPublicationYear "2013" @default.
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