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- W2363655769 abstract "In order to control the disease of Pelodiscus sinensis caused by Aeromonas hydrophila through the way of immune prevention,sustained-release microspheres vaccine was prepared by emulsionsolvent diffusion method.The immune response was determined after intragastric administration.The range of the turtles body weight was 150-200g,the dose was 0.1g/individual,and 6.75×1010/g inactivated bacteria was coated in 1g microsphere.The result of immune response showed that the duration of microspheres release was 40d.The highest of serum antibody titer,leucocyte phagocytic rate,leucocyte phagocytic index,and lymphocyte transformation rate of the oral experimental group could reach 512, 71.25%,1.51and 77.25%,respectively.The immune response of the turtle via intragastric administra-tion of sustained-release microsphere vaccine was similar to that injected with inactivated A.hydrophila, and the immune response after oral administration could persist longer than injection.The turtle was immunized via intragastric(0.1g/individual)or injection administration,and then challenge test was carried out.Relative protection rate of the turtle immunized by oral and injection administration were both 85%. The immune response experiment and challenge test could demonstrate the steadiness and validity of the sustained-release microsphere vaccine." @default.
- W2363655769 created "2016-06-24" @default.
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- W2363655769 date "2014-01-01" @default.
- W2363655769 modified "2023-09-23" @default.
- W2363655769 title "Preparation of Aeromonas hydrophila sustained release microspheres vaccine and its immune effectiveness" @default.
- W2363655769 hasPublicationYear "2014" @default.
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