Matches in SemOpenAlex for { <https://semopenalex.org/work/W2363663776> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2363663776 abstract "AIM: To determine the importance of SR-AI/II in the removal of modified low density lipoprotein (LDL) from the bloodstream in vivo. METHOD:To observe the clearance rate of modified LDL in the plasma of SR-AI/II knockout and control mice. RESULTS: Clearance rate from plasma of oxidized LDL in normal mice was very rapid, and over 90% of injected dose was removed from the blood within 5 minutes. Clearance rates of oxidized LDL were equally high in SR-AI/II gene knockout mice. Similarly, there was no difference in the clearance rate of acetyl LDL in wild-type and SR-AI/II gene knockout animals. The plasma clearance or radio-iodinated acetyl LDL was almost fully blocked by a 50-folds excess of unlabelled acetyl LDL, but the latter only inhibited oxidized LDL clearance by about 5%. Both AC-LDL and OX-LDL were mostly cleared from plasma by the liver. There was no difference in the tissue distribution of modified LDL in control and knockout mice. CONCLUSION: SR-AI/II does not play a significant role in the removal of oxidized LDL from plasma." @default.
- W2363663776 created "2016-06-24" @default.
- W2363663776 creator A5009897365 @default.
- W2363663776 date "1999-01-01" @default.
- W2363663776 modified "2023-09-25" @default.
- W2363663776 title "The clearance of oxidized-LDL and acetylated-LDL in AI/II scavenger receptor knockout mice" @default.
- W2363663776 hasPublicationYear "1999" @default.
- W2363663776 type Work @default.
- W2363663776 sameAs 2363663776 @default.
- W2363663776 citedByCount "0" @default.
- W2363663776 crossrefType "journal-article" @default.
- W2363663776 hasAuthorship W2363663776A5009897365 @default.
- W2363663776 hasConcept C104317684 @default.
- W2363663776 hasConcept C112705442 @default.
- W2363663776 hasConcept C126322002 @default.
- W2363663776 hasConcept C126894567 @default.
- W2363663776 hasConcept C134018914 @default.
- W2363663776 hasConcept C138944611 @default.
- W2363663776 hasConcept C150903083 @default.
- W2363663776 hasConcept C170493617 @default.
- W2363663776 hasConcept C18206936 @default.
- W2363663776 hasConcept C182704531 @default.
- W2363663776 hasConcept C185592680 @default.
- W2363663776 hasConcept C207001950 @default.
- W2363663776 hasConcept C2778163477 @default.
- W2363663776 hasConcept C2779620165 @default.
- W2363663776 hasConcept C2780072125 @default.
- W2363663776 hasConcept C3018403923 @default.
- W2363663776 hasConcept C41443022 @default.
- W2363663776 hasConcept C43554185 @default.
- W2363663776 hasConcept C55493867 @default.
- W2363663776 hasConcept C71924100 @default.
- W2363663776 hasConcept C77957584 @default.
- W2363663776 hasConcept C86803240 @default.
- W2363663776 hasConceptScore W2363663776C104317684 @default.
- W2363663776 hasConceptScore W2363663776C112705442 @default.
- W2363663776 hasConceptScore W2363663776C126322002 @default.
- W2363663776 hasConceptScore W2363663776C126894567 @default.
- W2363663776 hasConceptScore W2363663776C134018914 @default.
- W2363663776 hasConceptScore W2363663776C138944611 @default.
- W2363663776 hasConceptScore W2363663776C150903083 @default.
- W2363663776 hasConceptScore W2363663776C170493617 @default.
- W2363663776 hasConceptScore W2363663776C18206936 @default.
- W2363663776 hasConceptScore W2363663776C182704531 @default.
- W2363663776 hasConceptScore W2363663776C185592680 @default.
- W2363663776 hasConceptScore W2363663776C207001950 @default.
- W2363663776 hasConceptScore W2363663776C2778163477 @default.
- W2363663776 hasConceptScore W2363663776C2779620165 @default.
- W2363663776 hasConceptScore W2363663776C2780072125 @default.
- W2363663776 hasConceptScore W2363663776C3018403923 @default.
- W2363663776 hasConceptScore W2363663776C41443022 @default.
- W2363663776 hasConceptScore W2363663776C43554185 @default.
- W2363663776 hasConceptScore W2363663776C55493867 @default.
- W2363663776 hasConceptScore W2363663776C71924100 @default.
- W2363663776 hasConceptScore W2363663776C77957584 @default.
- W2363663776 hasConceptScore W2363663776C86803240 @default.
- W2363663776 hasLocation W23636637761 @default.
- W2363663776 hasOpenAccess W2363663776 @default.
- W2363663776 hasPrimaryLocation W23636637761 @default.
- W2363663776 hasRelatedWork W106704647 @default.
- W2363663776 hasRelatedWork W1550638578 @default.
- W2363663776 hasRelatedWork W1837608239 @default.
- W2363663776 hasRelatedWork W1972413425 @default.
- W2363663776 hasRelatedWork W1986139246 @default.
- W2363663776 hasRelatedWork W1987525850 @default.
- W2363663776 hasRelatedWork W1996548712 @default.
- W2363663776 hasRelatedWork W2025811736 @default.
- W2363663776 hasRelatedWork W2079884939 @default.
- W2363663776 hasRelatedWork W2081393029 @default.
- W2363663776 hasRelatedWork W2102161788 @default.
- W2363663776 hasRelatedWork W2109738937 @default.
- W2363663776 hasRelatedWork W2114467084 @default.
- W2363663776 hasRelatedWork W2118600056 @default.
- W2363663776 hasRelatedWork W2151345420 @default.
- W2363663776 hasRelatedWork W2164001634 @default.
- W2363663776 hasRelatedWork W2168115093 @default.
- W2363663776 hasRelatedWork W2170522996 @default.
- W2363663776 hasRelatedWork W2172113087 @default.
- W2363663776 hasRelatedWork W2193515894 @default.
- W2363663776 isParatext "false" @default.
- W2363663776 isRetracted "false" @default.
- W2363663776 magId "2363663776" @default.
- W2363663776 workType "article" @default.