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- W2363668158 abstract "Objective: To investigate the effect of Huang Jin Fang in the prevention and treatment of influenza A H1N1 virus strain FM1 and strain PR8 infection in mice.Methods: Viral pneumonia was induced by intranasal infection with influenza virus in the normal and immunosuppressed mice.The mice were treated with Huang Jin Fang before and after infection,respectively.The changes in pulmonary index,mortality and life span of mice were compared among groups after medication.Results: Huang Jin Fang 3 and 6 g·kg-1 markedly decreased pulmonary index after infection in the normal mice compared with control group(P0.05),and all the doses(1.5,3 and 6 g·kg-1) significantly reduced mortality as well as prolonged survival time compared with infection control(P0.01).The doses of 3 and 6 g·kg-1 markedly decreased pulmonary index after infection in the immunosupressed mice compared with infection control(P0.05);significantly reduced mortality as well as prolonged survival time compared with infection control(P0.01).Conclusion: Huang Jin Fang has a remarkable effect in the treatment and prevention of influenza virus infection in mice." @default.
- W2363668158 created "2016-06-24" @default.
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- W2363668158 date "2011-01-01" @default.
- W2363668158 modified "2023-09-26" @default.
- W2363668158 title "Effect of Huang Jin Fang in the prevention and treatment of influenza A H_1N_1 virus in mice" @default.
- W2363668158 hasPublicationYear "2011" @default.
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