Matches in SemOpenAlex for { <https://semopenalex.org/work/W2363697763> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W2363697763 abstract "Flurbiprofen liposomes were prepared by thin film evaporation and ultrasonic technique.The encapsulation efficiency and drug loading of flurbiprofen liposomes were determined with the protamine aggregation method.The impact factors on drug carrying characteristics of flurbiprofen liposomes were discussed.The results indicate that flurbiprofen liposomes have good dispersion and their average diameter are about 100-250 nm.Flurbiprofen molecules were located in the hydrophobic group region of liposomes and the partition coefficient KD of flurbiprofen between the liposomes and the aqueous phase was 815.6.The obtained liposomes have better entrapment efficiency and drug loading when the concentration of lecithin is 5.4×10-4 mol·L-1.With the increase of flurbiprofen/lecithin mass ratio,the drug loading of flurbiprofen liposomes increases,while its encapsulation efficiency decreases.Cholesterol can adjust the stability of liposomal membrane and the mass ratio of cholesterol to lecithin should be lower than 0.3.However,higher cholesterol concentration makes a great amount of cholesterol insert into membrane and leads to larger membrane rigidity,which decreases the entrapment efficiency and drug loading of liposomes." @default.
- W2363697763 created "2016-06-24" @default.
- W2363697763 creator A5079847700 @default.
- W2363697763 date "2011-01-01" @default.
- W2363697763 modified "2023-09-23" @default.
- W2363697763 title "Preparation and Drug Carrying Characteristics of Flurbiprofen Liposomes" @default.
- W2363697763 hasPublicationYear "2011" @default.
- W2363697763 type Work @default.
- W2363697763 sameAs 2363697763 @default.
- W2363697763 citedByCount "0" @default.
- W2363697763 crossrefType "journal-article" @default.
- W2363697763 hasAuthorship W2363697763A5079847700 @default.
- W2363697763 hasConcept C178790620 @default.
- W2363697763 hasConcept C185154212 @default.
- W2363697763 hasConcept C185592680 @default.
- W2363697763 hasConcept C2776681766 @default.
- W2363697763 hasConcept C2779564620 @default.
- W2363697763 hasConcept C2779820397 @default.
- W2363697763 hasConcept C2781000538 @default.
- W2363697763 hasConcept C41625074 @default.
- W2363697763 hasConcept C43617362 @default.
- W2363697763 hasConcept C55493867 @default.
- W2363697763 hasConcept C71924100 @default.
- W2363697763 hasConcept C98274493 @default.
- W2363697763 hasConceptScore W2363697763C178790620 @default.
- W2363697763 hasConceptScore W2363697763C185154212 @default.
- W2363697763 hasConceptScore W2363697763C185592680 @default.
- W2363697763 hasConceptScore W2363697763C2776681766 @default.
- W2363697763 hasConceptScore W2363697763C2779564620 @default.
- W2363697763 hasConceptScore W2363697763C2779820397 @default.
- W2363697763 hasConceptScore W2363697763C2781000538 @default.
- W2363697763 hasConceptScore W2363697763C41625074 @default.
- W2363697763 hasConceptScore W2363697763C43617362 @default.
- W2363697763 hasConceptScore W2363697763C55493867 @default.
- W2363697763 hasConceptScore W2363697763C71924100 @default.
- W2363697763 hasConceptScore W2363697763C98274493 @default.
- W2363697763 hasLocation W23636977631 @default.
- W2363697763 hasOpenAccess W2363697763 @default.
- W2363697763 hasPrimaryLocation W23636977631 @default.
- W2363697763 hasRelatedWork W1520756134 @default.
- W2363697763 hasRelatedWork W1993363718 @default.
- W2363697763 hasRelatedWork W2026937857 @default.
- W2363697763 hasRelatedWork W2028330493 @default.
- W2363697763 hasRelatedWork W2048751145 @default.
- W2363697763 hasRelatedWork W2057295294 @default.
- W2363697763 hasRelatedWork W2122205953 @default.
- W2363697763 hasRelatedWork W2157634286 @default.
- W2363697763 hasRelatedWork W2182409358 @default.
- W2363697763 hasRelatedWork W2187124263 @default.
- W2363697763 hasRelatedWork W2197598583 @default.
- W2363697763 hasRelatedWork W2266737611 @default.
- W2363697763 hasRelatedWork W2368928059 @default.
- W2363697763 hasRelatedWork W2375125656 @default.
- W2363697763 hasRelatedWork W2379268588 @default.
- W2363697763 hasRelatedWork W2389906034 @default.
- W2363697763 hasRelatedWork W2746277917 @default.
- W2363697763 hasRelatedWork W2794229994 @default.
- W2363697763 hasRelatedWork W3097021983 @default.
- W2363697763 hasRelatedWork W3170024363 @default.
- W2363697763 isParatext "false" @default.
- W2363697763 isRetracted "false" @default.
- W2363697763 magId "2363697763" @default.
- W2363697763 workType "article" @default.