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- W2363706754 abstract "Objective To investigate if the imbalance of sex hormone levels exists in female patients with hypothyroidism or Graves disease,and to explore the relationship between sex hormone level changes and thyroid dysfunction.Methods Serum testosterone(TT),estradiol(E2),follicle stimulating hormone(FSH),leuteinizing hormone(LH) was detected with radioimmunoassay,and the sex hormone binding globulin capacity(SHBG) was tested with ammonium sulfate precipitation.Results The patients in hypothyroidism group had lower TT [(1.70±0.60) ng/ml vs(2.60±0.30) ng/ml] and E2 [(0.08±0.01) pg/ml vs(0.12±0.02) pg/ml](P0.05) but significantly higher FSH [(18.12 ± 1.30) mIU/L vs(11.30±1.60) mIU/L] and LH [(32.89±21.64) mIU/L vs(9.70±1.00) mIU/L](P0.01) level than the ones in control group.And FSH[(15.20±1.10) mIU/L vs(11.30±1.60) mIU/L],LH[(18.30±1.70) mIU/L vs(9.70±1.0) mIU/L],TT[(4.20±0.30) ng/ml vs(2.60±0.30) ng/ml],E2[(0.29±0.02) pg/ml vs(0.12±0.02) pg/ml] level from patients in GD group was found increased compared with that from patients in control group.The difference was statistical in FSH and TT(P0.05),but LH and E2 level was significantly defferent with that in control group(P0.01),the change difference of SHBG in hypothyroidism and GD group were significantly(P 0.01).Conclusion Disordered serum sex hormone is found in female patients with hypothyroidism and Graves disease." @default.
- W2363706754 created "2016-06-24" @default.
- W2363706754 creator A5059373839 @default.
- W2363706754 date "2013-01-01" @default.
- W2363706754 modified "2023-09-23" @default.
- W2363706754 title "Analysis on serum sex hormone level changes of female patients with hypothyroidism or Graves disease" @default.
- W2363706754 hasPublicationYear "2013" @default.
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