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- W2363719405 abstract "OBJECTIVE To optimize the formulations of Artemisia rupestria dropping pill using D-optimal mixture design. METHODS Taking the drug loading,the amounts of PEG4000 and PEG6000 as investigation factors,and weight coefficient of variation,dissolution time,appearance(spherical degree,color,hardness)as assessment index,D-optimal mixture design was applied to optimize the formulation of Artemisia rupestria dropping pill.RESULTS The results showed the optimized proportioning was drug∶PEG4000∶PEG6000 of 14.0%∶12.0%∶74.0%.CONCLUSION Preparing the dropping pills with optimized prescription has good pharmaceutic reproducibility.To optimize prescription of Artemisia rupestria dropping pill with D-optimal mixture experimental design is feasible." @default.
- W2363719405 created "2016-06-24" @default.
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- W2363719405 date "2014-01-01" @default.
- W2363719405 modified "2023-09-23" @default.
- W2363719405 title "Optimization of the formulations of Artemisia rupestria dropping pill using D-optimal mixture design" @default.
- W2363719405 hasPublicationYear "2014" @default.
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